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| LEVOBUNOLOL HYDROCHLORIDE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 47141-42-4 |
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| EINECS NO. | ||
| FORMULA | C17H25NO3·HCl | |
| MOL WT. | 327.85 | |
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H.S. CODE |
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| SMILES |
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| SYNONYMS | ||
| (-)-5-[3,(t-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1(2H)-naphthalenone; | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | white to pink powder | |
| MELTING POINT | 205 - 210 C | |
| BOILING POINT | ||
| SPECIFIC GRAVITY | ||
| SOLUBILITY IN WATER | ||
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SOLVENT SOLUBILITY |
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| pH | 4.5 - 6.5 (5% solution) | |
| VAPOR DENSITY |
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| AUTOIGNITION |
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| NFPA RATINGS | ||
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY |
Stable under ordinary conditions. |
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APPLICATIONS |
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| Levobunolol is an ophthalmic beta-adrenergic blocking agent used to treat ocular hypertension and open-angle glaucoma as an antihypertensive and antianginal in eyes. It is chemically described as (-)-5-[3,(t-Butylamino)-2-hydroxypropoxy]- 3,4-dihydro-1(2H)- naphthalenone; white to pint powder. Hydrochloride salt of levobunolol is for the formulation of ophthalmic solution (eye drops). Other ophthalmic beta-adrenergic blocking agents include betaxolol, carteolol, levobetaxolol, metipranolol and timolol. | ||
| SALES SPECIFICATION (USP) | ||
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APPEARANCE |
white to pink powder | |
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IDENTIFICATION |
Complies
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ASSAY |
98.5 - 101.0% |
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MELTING POINT |
205 - 210 C | |
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RESIDUE ON IGNITION |
0.1% max |
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HEAVY METALS |
10ppm max |
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pH |
4.5 - 6.5 (5% solution) | |
| TRANSPORTATION | ||
| PACKING |
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| HAZARD CLASS | ||
| UN NO. | ||
| PRICE INFORMATION | ||
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